The Chargers (1-1) are trying to return to the playoffs again this season but the Bills (2-0) are not about to lay down after pulling off back to back wins against the Bears and Dolphins to start the season.
Coverage of the game between the Chargers and Bills will air on CBS beginning at 1:00 pm ET from Ralph Wilson Stadium in Buffalo, NY.
The Odds: The Buffalo Bills are a 2.5 point favorite against the San Diego Chargers. The over/under for this game is 44.5 total points.
Will it be the Bills or the Chargers who find victory on Sunday?