Manuel has been given the green light to practice but Bills head coach Doug Marrone will ultimately determine if the first-round pick will play in Week 10 against the Steelers.
The Bills have been without Manuel since he suffered a knee injury on Oct. 3 against Cleveland.
EJ Manuel says he's been cleared to practice. Decision to play up to Marrone, he says
— Mike Rodak (@mikerodak) November 4, 2013
Without Manuel the Bills offense has been sluggish with Thad Lewis and Jeff Tuel under center.
During his first five games,Manuel had a 56.7 completion percentage with 985 yards passing, five touchdowns and three interceptions.