Up by six the Indianapolis Colts were hoping to avoid being on the wrong side of a Peyton Manning comeback. Faced with a 3rd-and-1 the Colts went to the air.
Quarterback Andrew Luck badly under threw a wide open Reggie Wayne who went down trying to make a move the ball.
The result was Wayne going down to the turf at Lucas Oil Stadium. He was helped off the field with the Colts training staff and later limped to the locker room.
Wayne was ruled out of the game with a knee sprain. More information should be forthcoming. The Colts have a bye next week.
