Denver Broncos vs. Indianapolis Colts: Betting odds, point spread and tv info

INDIANAPOLIS, IN - OCTOBER 20:  Andrew Luck #12 of the Indianapolis Colts and Peyton Manning #18 of the Denver Broncos meet after the game at Lucas Oil Stadium on October 20, 2013 in Indianapolis, Indiana. The Colts won 39-33. (Photo by Andy Lyons/Getty Images)

 (Photo by Andy Lyons/Getty Images)

In a game that always generates a lot of interest the Denver Broncos will travel to take on the Indianapolis Colts.

While the Colts (3-5) are the AFC South leaders this game has interest simply because of Broncos (7-0) quarterback Peyton Manning returning to Indianapolis. The Colts desperate for changes fired offensive coordinator Pep Hamilton earlier this week. Coverage of this game will air on CBS beginning at 4:25 pm ET from Lucas Oil Stadium in Indianapolis, IN.

The Odds: The Broncos are 5 point favorites against the Colts. The over/under for this game is 45 total points.

Will Manning get the better of his old team or does Andrew Luck and company pull off the upset in this one?